General description

LNE CRM Bio 301 is a higher-order certified reference material produced by the French metrological institute LNE in compliance with ISO 17034 requirements. This secondary standard is intended for use as quality control material to assess the measurement bias or measurement uncertainty of established or new measurement procedures for the determination of creatinine, glucose, total cholesterol, total glycerides, HDL-cholesterol and LDL-cholesterol in human serum. The Certified Reference Material LNE CRM Bio 301 corresponds to a pool of Human Frozen Serum that was prepared according to the Clinical Laboratory Standards Institute (CLSI) C37-A guidelines describing the preparation and validation of commutable frozen human serum pools as Secondary Reference Materials for Cholesterol Measurement. Samples commutability was assessed through a commutability study involving several clinical laboratories. Commutability results are reported in the certificate of analysis.